Clinical application of the principles of weaning from invasive ventilation in very preterm infants

Mechanical ventilation in newborns increases the risk of bronchopulmonary dysplasia and poor neontal outcomes. Early extubation is a desirable treatment option, but premature and unprepared extubation is dangerous. Extubation was performed in 146 newborns with a gestational age of less than 27 weeks (57 children) and 27-31 weeks (89 children). Extubation readiness criteria and non invasive intermittent positive pressure ventilation and high frequency oscillatory ventilation were applied. The frequency of forced reintubation within 5 days after extubation is at the level of 21-22%.