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Юрий Владимирович Дадали
North-Western State Medical University named after I.I. Mechnikov 191015, St. Petersburg; 195067, St. Petersburg
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Владимир Абдуллаевич Дадали
North-Western State Medical University named after I.I. Mechnikov 191015, St. Petersburg; 195067, St. Petersburg
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Дмитрий Юрьевич Кормилец
Military Medical Academy named after S.M. Kirov 194044, St. Petersburg
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Александр Тимурович Марьянович
Military Medical Academy named after S.M. Kirov 194044, St. Petersburg
Abstract
Antibiotic peptides are the main line of defense of the human innate immunity system and are potentially active against a wide range of pathogenic microorganisms, including gram positive and gram negative bacteria, mycobacteria, spirochetes, fungi, viruses and protozoa. The review highlights the mechanisms of interaction of antibiotic peptides with cell membranes and intracellular targets of microorganisms. Briefly discussed are the methods of interaction of these substances with viruses and toxins, as well as the mechanisms of resistance of microorganisms to antibiotic peptides.
Author Biographies
Юрий Владимирович Дадали, North-Western State Medical University named after I.I. Mechnikov 191015, St. Petersburg; 195067, St. Petersburg
Piskarevsky, 47
Владимир Абдуллаевич Дадали, North-Western State Medical University named after I.I. Mechnikov 191015, St. Petersburg; 195067, St. Petersburg
Piskarevsky, 47
Дмитрий Юрьевич Кормилец, Military Medical Academy named after S.M. Kirov 194044, St. Petersburg
Academician Lebedev str., 6
Александр Тимурович Марьянович, Military Medical Academy named after S.M. Kirov 194044, St. Petersburg
Academician Lebedev str., 6; Candidate of Medical Sciences, Doctor of Biological Sciences, Professor, Head Department of Normal Physiology.
